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Tay-Sachs Disease

Across
Decreased muscle tone. (symptom associated with Tay-Sachs)
Asymmetric lower limb motor neuropathy (symptom associated with Tay-Sachs)
Fatty substance in the brain that destroys nerve cells
Autosomal recessive disease caused by mutations in both alleles of HEXA gene on
Sometimes Tay-Sachs is called this
proteins that are found within the cell
Heterogeneous group of inherited disorders of lipid metabolism affecting primarily the central nervous system
Muscles stiffen or tighten, preventing normal fluid movement (symptom of Tay-Sachs)
Memory loss (symptom of Tay-Sachs)
Down
The mutation that causes Tay-Sachs on chromosome 15
A change in DNA sequence
Burst of uncontrolled electrical activity between brain cells (symptoms of Tay-Sachs disease)
Muscle twitching (symptom of Tay-Sachs disease)
The organelle associated with Tay-sachs disease- contains digestive enzymes
Slurred speech (symptom of Tay-Sachs disease)
Difficulty swallowing (symptom of Tay-sachs)
Control and the coordination of all parts of the body