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Ch. 10 Vocabulary

Across
Genetic ____- identifying gene variants in an individual that may lead to a genetic disease in that individual
____ DNA- a combination of DNA fragments generated by molecular cloning that does not exist in nature
in molecular biology, the process by which two single strands of DNA hydrogen bond at complementary nucleotides to form a double-stranded molecule
the use of artificial methods to modify the genetic material of living organisms or cells to produce novel compounds or to perform new functions
an organism whose genome has been artificially changed (abbreviated)
___ cloning- cloning of entire organisms
____ organism- a species that is studied and used as a model to understand the biological processes in other species represented by the model organism
the study of drug interactions with the genome or proteome; also called toxicogenomics
study of the function of proteomes
____ map- a representation of the physical distance between genes or genetic markers
Protein ___- a set of over- or under-expressed proteins characteristic of cells in a particular diseased tissue
Whole genome ___- a process that determines the nucleotide sequence of an entire genome
the production of an exact copy—specifically, an exact genetic copy—of a gene, cell, or organism
Down
a technique used to make multiple copies of DNA (Abbreviated)
Genetic ___-an outline of genes and their location on a chromosome that is based on recombination frequencies between markers
describing an organism that receives DNA from a different species
Genetic _____- alteration of the genetic makeup of an organism using the molecular methods of biotechnology
Gel ______-a technique used to separate molecules on the basis of their ability to migrate through a semisolid gel in response to an electric current
the study of entire genomes, including the complete set of genes, their nucleotide sequence and organization, and their interactions within a species and with other species
the study of the collective genomes of multiple species that grow and interact in an environmental niche
an individual protein that is uniquely produced in a diseased state
____ enzymes- an enzyme that recognizes a specific nucleotide sequence in DNA and cuts the DNA double strand at that recognition site, often with a staggered cut leaving short single strands or “sticky” ends
___ genetics- a form of genetic analysis that manipulates DNA to disrupt or affect the product of a gene to analyze the gene’s function
Gene ____- the technique used to cure heritable diseases by replacing mutant genes with good genes
a small circular molecule of DNA found in bacteria that replicates independently of the main bacterial chromosome; plasmids code for some important traits for bacteria and can be used as vectors to transport DNA into bacteria in genetic engineering applications