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PALLIATIVE CARE PUZZLE #2: APPROACH TO ADJUVANTS

https://crosswordhobbyist.com/771532/PALLIATIVE-CARE-PUZZLE-2-APPROACH-TO-ADJUVANTS
Across
SNRI used for fibromyalgia pain; not subsidized in NZ
Muscle relaxant used for spasticity
Class of medication used to prevent steroid-related GI bleeding; only use if high bleeding risk
Receptor targeted by products like marijuana and associated with appetite, pain sensation, mood, and memory
Intense anger
Prickling or stinging neuropathic sensation
Toxin injected to alleviate refractory musculoskeletal pain, spasm, or dystonia
Air circulation device thought to palliate dyspnoea via CNV stimulation
Nervy pain
If the shoe ___
Risk of steroids
Alpha agonist that can be given by oral, transdermal, IV, epidural, or intrathecal route for adjuvant pain relief
___ good things must come to an end
Sealed road
Proctalgia ___, functional anorectal pain
Measure of concentration and strength of a substance in solution
Class that includes nortriptyline, multipurpose adjuvant that can improve pain, mood, sleep, and appetite
Relaxing bath
Class of drug used to manage hypercalcaemia or pain related to increased osteoclast activity
Local anaesthetic cream or patch
Commercials, for short
Somatostatin analogue used in bowel obstruction management
Benzodiazepine used for muscle spasms; limited evidence and potential for misuse
Another word for malignancy
Steroid known as "poor man's radiotherapy"
Greek prefix meaning "on" or "on top of"
Vasodilator used to relieve angina
Avoid capsaicin after this type of shower
Receptor targeted by drugs like ketamine
Novel benzenoid opioid under development
Can be suppressed by chronic steroid use
Believe it or ___
Topical preparation of diclofenac available over the counter
Ziconotide is a synthetic, non-opioid peptide analogue derived from this snail secretion
Mediator between the conscious and the unconscious, according to Freud
Brand name for Nabiximols mouth spray, cannabis extract approved for MS-related spasticity
Down
Asked by a rabbit: "what's up, ___?"
To pierce, stab, or tear
Three of a kind
From the Greek for "new"
___ pulmonale; right heart failure resulting from pulmonary disease
Not down
Antiviral used to treat influenza and Parkinsons; may reduce pain, allodynia, and hyperalgesia in select patients with neuropathy
Someone might go out on it
Common location for diabetic neuropathy
An adjuvant medication is one with a primary non-analgesic indication that can alleviate this
Less evolved sibling of 69 across
Pain in the chest
Sister, sometimes of the flying variety
Disturbing side effect of ketamine
Atypical antipsychotic that may decrease pain intensity and opioid consumption in malignancy, can also palliate delirium and nausea
Abbreviated expression of gratitude
Pertaining to the ear
Drug increasingly being used as an adjuvant with other opioids for complex cancer pain - may have a syngergistic effect
Spanish "one"
Subcutaneous medication given every 4 weeks to prevent complications from bone metastases; Xgeva
Nitrous oxide gas, for giggles
Anti-convulsant used to manage trigeminal neuralgia
Anticonvulsant often given three times per day for neuropathic pain
Deemed worthy
Illustrated pain scale
Iceberg's edge
Try this on for ___
Not against
Topical menthol brand
NMDA receptor antagonist used for adjuvant pain, but with strongest data for rapidly improving suicidality
Half, to a Greek
NSAID used for bone pain or inflammation
Enzyme targeted by 49 Down, briefly
Drugs like dronabinol are used to boost appetite, but much of the weight gain is this
Descriptor for knife-like pain
Ibuprofen and naproxen
The loneliest number, according to Three Dog Night
Common cancer metastasis site; pain can be palliated with radiotherapy, steroids, NSAIDs, etc
Often much about nothing
RICE for sprains: ___, ice, compression, elevation
Not young
Antonym of stop