Chronic disease of this organ is often associated with glucose intolerance and diabetes.
A hormone that produces predominantly neuroendocrine inhibitory effects across multiple systems.
These are somatostatin-producing cells of the pancreas.
This hormone directly impacts the liver as it works to control blood sugar levels.
Cells in the pancreas that produce, store and release the hormone insulin.
A condition caused by an imbalance in contractile protein synthesis and degradation which can be triggered by various conditions including Type 2 Diabetes.
An intracellular neutral lipase that is capable of hydrolyzing triacylglycerols, diacylglycerols, monoacylglycerols, and cholesteryl esters, as well as other lipid and water soluble substrates.
defined where a normal or elevated insulin level produces an attenuated biological response;2 classically this refers to impaired sensitivity to insulin mediated glucose disposal.
These accomplish the movement of glucose from the extracellular space into the cell.
Diabetes pathology derives from the combination of hyperglycemia and __________.
Pancreatic cells that secrete glucagon.
A peptide hormone secreted by the β cells of the pancreatic islets of Langerhans and maintains normal blood glucose levels by facilitating cellular glucose uptake.
A condition caused by a very low level of blood sugar (glucose).
Hormone that is co-secreted with insulin from the pancreatic β-cell.
Down
This enzyme is thought to contribute to degradation and clearance of insulin.
This disease results from the buildup of fats, cholesterol and other substances in and on your artery walls.
A serious diabetes complication where the body produces excess ketones.
Nerve damage caused by chronically high blood sugar and diabetes.
When blood-glucose levels are high, insulin stimulates this by triggering a pathway that activates protein phosphatase 1.
A defining characteristic of diabetes—when the blood glucose level is too high because the body isn't properly using or doesn't make the hormone insulin.
This condition has a strong relationship to diabetes and insulin resistance.
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