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Opioids

Across
An opium flowering plant (Daniel, para 1).
At this time the United States was trying to stop the distribution of the opioids for pain relief (Sanna, para 38).
The compulsive, uncontrolled use of drugs even to the detriment of quality of life and health (Ho, J. D, para 8).
The percent that went up when people died because of using this for chronic pain then suicide (MacCallum, para 10).
Not only were they used for pain relief but they were also used for birdseeds (Sanna, para 34).
The Oregon Health Authority reported methamphetamine- related deaths in 2016 exceeded those during the peak of the meth crisis of the early 2000s (Singer, para 2).
adaptation to medically necessary drugs that may cause serious side effects upon withdrawal (Ho, J. D, para 6).
In Western Europe the that has the lowest opioid overdose in the world, the reduction % (Singer, para 13).
The drug, Oxycontin, is manufactured by this contributor that made the opioid crisis an issue today(Gale, Para 5).
Introduced guidelines for physicians that set more appropriate standards for prescription drugs (Gale, para 10).
This person wrapped up a two month long trial of pharmaceutical Johnson & Johnson that made new light for opioid drugs (Mcgreal, Para 3).
First marketed in 1996, as a painkilling medicine (MacCallum, para 16).
Down
A synthetic drug with many of the same effects and addictive properties of opiates; sometimes used more broadly to include both synthetic opiate-like drugs and opiates ( Ho, J. D, Para 8).
A company paid the largest-ever over the opioid epidemic—$1.4bn—to settle a federal indictment accusing it of practices similar used by Purdue Pharma and Johnson; Johnson (Mcgreal, para 23).
She specializes in patients that have been in severe car accidents. One of her patients took so many opioids that she didn't realize an alarm was going off (MacCallum, para 28).
Codeine was the next to be extracted in this date by the pharmacist Pierre-Jean Robiquet (Sanna, para 24).
Powerful and much desired pain killer (Daniel, para 6).
The date The Soviet invasion of Afghanistan at this time enabled the rapid growth of opium production and trafficking ( Daniel, para 10).
The sharp recent rise in the number of Americans who abuse or are addicted to opioids (Gale, para 1).
CEO was the highest paid executive in the US as opioid deliveries reached their peak (Mcgreal, para 6).
Authorities reduced the opioid production, so non-medical users found another solution called (Singer, para 11):