After synthesis of the eukaryotic primary RNA transcript, the removal of portions of the transcript (introns-left behind in the nucleus)will not be included in transport to cytoplasm. Also, the joining of the exons (remaining portions) for transport.
Modification of RNA primary transcripts, including splicing out of introns, joining together of entrons and the alteration of the 5' and 3' ends.
A sequence of 50-250 adenine nucleotides added onto the 3' end of a pre-mRNA molecule to protect it from degradation. (by hydrolytic enzymes.) AAA:AAA:AAA
Complex of transcription factors and RNA polymerase II bind to the promoter.
A discrete structural and functional region of a protein. Also, a taxonomic category above a kingdom level. The three domains are Archaea, Bacteria and Eukarya.
Noncoding segments of nucleic acids that lie between coding regions on DNA/RNA strands are also called intervening sequences.
A sequence within a primary transcript that remains in the RNA after RNA processing; also refers to the DNA region from which this sequence was transcribed.
Down
A regulatory protein that binds to DNA and affects transcription of specific genes.
A modified form of guanine molecule nucleotide added onto the 5' end of a pre-mRNA molecule. Helps in exiting nucleus and helps ribosomes to attach to the 5'end in cytoplasm G-P-P-P
Signals end (STOP) pre-mRNA is cut and released when this appears and poly A-tail is added.
Refers to alternative RNA splicing. A type of eukaryotic gene regulation at the RNA-processing level in which different mRNA molecules are produced from the same primary transcript, depending on which RNA segments are treated as exons and which as introns.
A large complex made up of proteins and small RNA molecules that splices RNA by interacting with the ends of a RNA intron, releasing the intron and rejoining the exons.
An RNA molecule that functions as an enzyme; such as an intron that catalyzes its own removal during RNA splicing.
A DNA sequence in eukaryotic promoters crucial in forming the transcription initiation complex.
Untranslated regions of the mRNA at the 5' and 3'. Don't translate to protein. Downstream from cap and upstream from poly A-tail. Help bind to ribosomes. They are part of the exons.
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Where is my puzzle?
All your puzzles are accessible from your 'My Puzzles' page, which you can access using the navigation bar at the top when you are logged in.
Be sure to log in using the same email address you used when you created your puzzle.
How do I print?
There is a 'Make Printable' button on the top left of your puzzle that will let you sign up for a plan or purchase a single puzzle.
Once paid, that button will turn into a 'Preview + Publish' button that will put your puzzle in a format that can be printed or solved online.
Once you publish your puzzle, you can click the print icon or use your browser’s print function.
It looks weird when printed.
First make sure you’ve published your puzzle. See the 'How do I print?' section above for more information.
99% of other printing issues have to do with printer settings. Instead of trying to fiddle with printer settings, which can be time-consuming and frustrating, there are a couple workarounds you can try.
You can try printing from a different browser, since different browsers have different default print settings. Alternately, you can try saving as a PDF (next to the print icon) and print that.
Why isn’t this free?
We invested in building a number of premium features that free sites are unable to offer: the ability to automatically or manually add words to your puzzle, save-as-you-go puzzle editing, the ability to access your puzzles from any computer, an uncluttered and ad-free interface, the ability for friends and colleagues to solve your puzzles online, and quick responsiveness to reported issues.
My Crossword Maker is the lowest-price service we've found that provides these features, and is designed for people who are not satisfied with what free sites are able to provide.
I thought this was free.
We’re sorry you thought My Crossword Maker was free, that must have been frustrating.
We’re constantly trying to provide a clear and straightforward user experience, and we’re not trying to hide the price: on the page where you make your puzzle, the price is listed in the overview in the top left (before you log in), below the 'Make Printable' button (after you log in), in the FAQ below the grid, and also in the tour.
Unfortunately, we have limited control over how we show up in Google and on other sites, so if they show My Crossword Maker when someone searches for a free site we can’t do anything about that.
It says there is no account with my email.
First check whether you used a different email address to create your account. Your login email is the email address where you received a welcome email from us.
Alternately, it’s possible there was a typo in your email when you created your account. If so, report an issue below and provide the name and last four digits on the card you used when you signed up. We’ll use this information to track down your account.
I am being asked to pay a second time.
If you are a member of My Crossword Maker and are still being asked for payment, then you may have inadvertently created a second account.
Your paid account will have the email address where you received an email confirming your subscription.
If you never received such an email, or are still unable to find your paid account, report an issue below and provide the name and last four digits on the card you used when you signed up. We’ll use this information to track down your account.
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For security a human can’t see or reset your password, so read the below information carefully.
If you haven’t gotten the password reset email, check your spam folder, be sure you’re checking the email account that the email was sent to, and be aware that some school email systems block emails from non-school email addresses.
If you have the password reset email but the password isn’t accepted, be sure you are using the most recent password reset email: sometimes people will hit the button twice, and only the second password will work.
Be sure if you copy-paste the password not to get a space on the outside, or if you're typing it keep in mind that it's case-sensitive and that a lower-case L can look like the number 1, etc.
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Not all my words are in my puzzle.
When you hit the 'Arrange' button, our algorithm will try to arrange all your words on the grid, and will move words around to try to fit the most words.
This will get all the words on the grid about 90% of the time, depending on the word list. For the other 10%, you will get an alert explaining that the words that did not fit were added to the scratchpad.
It prints on two pages.
Big puzzles won’t always print on one page — the clues and grid are the smallest we could make them while keeping them readable for everyone.
That said, different browsers print in slightly different ways, so you could try using 'print preview' using a different browser (or try the PDF button) to see if you like how that looks better.
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We generally respond to all reported issues in about a day. If it’s been a few days and you haven’t heard back from us, it’s possible we sent an email that didn’t reach you.
Check your spam folder, and be aware that some school email systems block emails from non-school email addresses. Try providing a different email address if you think our emails to you are being blocked.
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