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Know Your Anticonvulsant Agents

Hint:  All clues refer to generic drug names
Across
Associated with oligohidrosis and hyperthermia
Contraindicated in patients with underlying cardiac arrhythmias
Requires dose adjustment for CY2C19 poor metabolizers
Prodrug of phenytoin with safer parenteral administration
Most commonly used to treat absence (petit mal) seizures
Causes hyponatremia
May lead to blindness and requires eye exam before prescribing
More than 1 out of 3 children may suffer behavioral abnormalities on this anticonvulsant
Lost FDA approval for children due to severe cutaneous hypersensitivity
Possible fatal multiorgan hypersensitivity
Potential cross reaction with sulfa allergic patients
Down
Causes coarsening of facial bones if used long term
Preferred benzodiazepine for intranasal administration
Known for its drug interactions involving metabolism, higher likelihood of hepatic dysfunction
Considered first line for neonatal seizures
Add to blood work for patients with known seizure history presenting with new seizure (two words)
Preferred benzodiazepine for single IV administration
May be used to induce a coma in status epilepticus unresponsive to GABA inhibition