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Chemo Drugs

Across
Anti-CD20 antibody, used in B-cell predominant cancers are severe autoimmune disorders, immunosuppression are the most common side effects.
Causes free radical formation with ROS cycling, inhibits topoisomerase II, and also has a cardiotoxic effect, creating a dose-limiting effect and cumulative toxicity.
Pyrimidine antagonist that quadrupled the survival rate in pancreatic cancer to 6%
A drug that is used to reduce hemorrhagic cystitis caused by cyclophosphamide
Down
Used for Philadelphia chromosome positive cancers, and causes bone marrow suppression.
Used for APL cancer, causes sensitivity to retinoid acid, dry skin, hepatotoxicity, and contraindicated in pregnancy
An antimetabolite chemotherapy drug that requires TB and PCP (pneumocystis carinii pneumonia) prophylaxis
Peptide antibiotic, iron and DNA binding sites, free radical formation transferred to DNA, and cumulative toxicity causing pulmonary fibrosis