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Pharmacological Principles

Lilley, L. L., Collins, S. R., & Snyder, J. S. (2019). Pharmacology and the nursing process (9th ed.). Mosby.
Across
The transport of a drug by the bloodstream to it's site of action.
A medication that prevents the activation of a receptor.
Needs more medication to get the same effect.
_____ level. The highest blood level of a drug.
An unpredicted overreaction or underaction to a medication, other than an allergic reaction.
______ effect. Unintended effects of medication that cause more discomfort rather than harm.
The extent of drug absorption.
________ effect. Two drugs given together that enhance the effects of one another.
Onset of _______. The time it takes for a drug to elicit a therapeutic response.
Once a drug binds to and interacts with the _______a pharmacological response occurs.
Down
The primary organ responsible for excretion.
Two parenteral drugs or solutions undergo a reaction when mixed or given together.
Drug ________ is the alteration of one drug by another.
Elimination of drugs from the body.
______ of action. The length of time the drug concentration is sufficient to elicit a therapeutic response.
------ level. The lowest blood level of a drug.
The study of what happens to a drug from the time it is taken until the time it is eliminated.
A state in which there is a compulsive or chronic need for a drug.
Changes a drug to an inactive by-product for excretion. Commonly occurs in the liver.
______ barrier. The barrier system that restricts the passage of chemicals and substances between the bloodstream and the central nervous system.
The movement of a drug from its site of administration into the bloodstream for distribution to the tissues.
The elimination of drugs from the body.
________ effect. A drug absorbed from the intestine must first pass through the liver before it reaches systemic circulation.
Reverses adverse bodily effects due to poisonous qualities of medications.
_______ drug effects are undesirable effects of a prescribed medication.
A drug that binds to and stimulates the activity of one or more receptors in the body.
The condition of producing adverse bodily effects due to poisonous qualities of medications. Occurs if the peak level of the drug is too high.