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Types of Antibiotics and Toxicity

Across
Antiviral drug that inhibits herpes virus DNA polymerase
Structurally related to PABA and competes with it for the active site of an enzyme involved in folic acid synthesis
Antiviral drug used to prevent influenza
First true antibiotic because it is a natural microbial product
Ability of the agent to kill or inhibit the pathogen as much as possible without damaging the host
Large group that inhibits protein synthesis by binding to the 30S small ribosomal subunit
Commonly prescribed for UTIs, inhibits DNA-gyrase and topoisomerase IV
Down
First broad-spectrum antibiotic, only used in life threatening situations
Family of antibiotics with a common four-ring structure
Produced from Streptomyces orientalis, previously known as "drug of last resort"
Can be combined with sulfa drugs to increase efficacy of treatment
Contains a 12-22 carbon lactone ring, contains Erythromycin