PMF is an uncommon bone marrow disorder that affects the blood cell production The healthy bone marrow tissue is replaced with a fibrous scar-like material which destroys the normal bone marrow over time.
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Reduction in the number of blood cells.
Removal of the spleen
Reduction in the haemoglobin level present in the body result in sever _____
_________are a broad and loose category of small proteins that are important in cell signaling
Changes in the blood cells that causes it to become cancerous
Allogenic stem cells transplants is associated with high risks and have a high rate of ______ and morbidity.
PMF is a disorder that disrupts the production of ______ in the bone marrow.
permanent alteration in the DNA sequence that makes up a gene
______mutation results in cell turnover which increases proliferation and cell division significantly
Patients often have a sever ______ due to low RBC
The disease is usually referred as _______ myelofibrosis as the cause is unknown
Tissue formation on the bone marrow
Down
_________is a type of chronic clonal myeloproliferative neoplasm disorder
A drug used for the treatment of intermediate primary myelofibrosis.
Bone marrow is damaged by a _______ which prevent it from producing healthy blood cells.
Function of red blood cells
_______ of all the blood cells will result in many symptoms including irregular bleeding, inflammation and others
If PMF is left untreated, the disease will progress and transforms into ________
Reduced number in white blood cells usually results in patients developing ______ easily
Patients are required to undergo ____________ to get rid of myelofibrosis and have healthy stem cells infused for a new healthy bone marrow production.
The disease is mostly common in the _______
Spleen usually takes over the role of production of blood cells and as a result it will become enlarged
A symptom that is caused by decreased number of platelets
It is used to view the shape of damaged blood cell to indicate the diagnoses of the disease
_______ support blood clotting to stop bleeding
The tissue found in the centre of our bones. _______ contains stem cells from which all blood cells are made
The disease is not influenced by other disorders and is caused on it's own
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