This may be the first symptom of a spinal cord compression in a patient
Most commonly seen in patients with lung cancer, breast cancer, and lymphoma patients. Symptoms: SOB, cough, pleuritic chest pain, anxiety. May be seen in patients receiving imatinib and dasatinib
Occurs in patients with malignancies associated with large tumor burdens or rapidly proliferating cells. Hyperkalemia, hyperuricemia, hyperphosphatemeia with hypocalcemia. may lead to acute renal failure. Prompt identification and treatment is essential
Tumor invades or extends into the epidural space or pathologically collapses vertebral bones.
Aka: Zoledronic acid. Used to treat hypercalcemia
Used to treat high uric acid levels associated with TLS
Down
Often caused by the pathologic destruction of the bone. Often seen in patients with bone mets or multiple myeloma. Initially symptoms may be non-specific, but may lead to neurological symptoms and/or kidney damage.
The presence of this places a patient at higher risk of developing superior vena cava syndrome
Patients with this disease may have cord compressions, hypercalcemia, renal failure.
Oncology patients have a higher risk for developing this. Cancer patients are estimated to have a five-fold higher incidence of developing these.
Play a key role in identification of oncologic emergencies and improving patient oucomes
Systemic inflammatory response to pathogenic micro-organisms and associated endotoxins in blood. Potentially life threatening. Early detection is essential. Occurs more frequently in patients with hematologic malignancies
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