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Sepsis

Across
Assessment based on a 3-point version of the SOFA, recommended to identify possible organ dysfunction and prompt timely evaluation for sepsis in a non-ICU setting. RR>/=20, altered mentation, SBP</=100mmHg
Administer 30cc/kg if SBP<90, LA>4
Should be completed within 3 hours, includes, LA, BCx2, Abx within 1 hour, 30cc/kg IVF bolus if SBP<90, LA >4 (repeat LA within 3 hour window)
The mortality rate of hospitalized patients with sepsis, a percentage
Annual hospital costs for treatment of sepsis in the US, in billions
Down
Identified in septic patients who have hypotension needing vasopressor therapy to maintain MAP >/=65 and a serum lactate >2mmol/L despite adequate fluid resuscitation.
Should be administered within 1 hour of possible sepsis identification.
A life-threatening organ dysfunction caused by simultaneous systemic inflammation and coagulation in response to microbial infection.
An elevated level reflects cellular dysfunction with higher degrees associated with increased mortality risk.