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Lymphatic System and Immunity

Across
Inner region = medulla; contains T cells (+ macrophages and plasma cells) arranged as ____ ____ (spaces through which lymph flows).
Outer region = cortex; contains densely packed B cells (+ macrophages) called _____ ____ (or follicles).
___ ___ vessels enter at points on the convex surface.
When B cells or T cells first encounter an antigen for which they are specialized to react, the reaction is called a____ immune response.
The thymus is a soft, bilobed organ located within the ____.
Allergic reaction which can occur in anyone and can cause inflammation of the skin, results from repeated exposure to antigenic substances (i.e household detergents, cosmetics).
A ____ T cell becomes activated when it encounters a displayed antigen (on macrophage) for which it is specialized to react.
blood plasma that has passed through cardiovascular capillary walls into interstitial spaces, minus large plasma proteins.
The secondary lymphatic organs that are the sites where most immune responses occur are the lymph nodes and the ____.
_____ are viruses and microorganisms (bacteria, fungi, protozoans, parasites) that cause disease.
____ T cells are produced upon initial exposure to an antigen.
Down
When lymphatic tissue is not encapsulated, it is called ____ ____ ____.
The thymus is the site of maturation of__ ___ (which will leave the thymus and provide immunity)
dissolved substances including small plasma proteins, nutrients, wastes, gases, electrolytes, enzymes and hormones.
When lymphatic tissue is aggregated into a solitary, oval-shaped mass, it is called a ____ ____.
In ____ ____, allergy mediators are responsible for the symptoms of the allergic reaction, including decreased blood pressure (vasodilation) and difficulty breathing (bronchoconstriction).
An autoimmune disease where antibodies attack acetylcholine receptors in skeletal muscle.
The primary lymphatic organs that are the sites of production of immunocompetent cells, B cells and T cells that can carry out an immune response are red bone marrow and the ____.
__ ___ provide Antibody-mediated (humoral) immunity.
Removal and destruction of potentially harmful foreign particles from lymph is accomplished through _____ by macrophages.
transports foreign particles to the lymph nodes and returns small leaked plasma proteins back to the blood stream.
_____ remove and destroy foreign particles from tissues and body fluids.
____attack antigens directly, activate complement, and stimulate local tissue changes that hinder antigen-bearing agents.
Node is enclosed in a dense CT ____ that extends into the node and subdivides it into nodules.
The size of lymph nodes is usually less than 2.5 cm, and shape is bean-like, with blood vessels, nerves, and efferent lymphatic vessels attached to the indented region, or the ____.
accumulation of excess interstitial fluid leading to swelling of tissues.