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Biostats review

Across
1) The degree to which the findings of a study are correct. (2) The extent to which an instrument measures what it is intended to measure.
The main outcome of interest in a research study. (2 words)
The overall plan that enables researchers to gather answers to study questions and test hypotheses.
Ethical principle of doing or producing good. In scientific research involving human subjects, actions are taken to protect the public from harm and to maximize possible benefits and minimize possible harms.
Part of a journal article or research report that describes the research findings based on the statistical analyses. (2 words)
Experimental trial that involves the use of a drug with subjects with the disease in question. These trials are designed to give initial data on efficacy and continued safety/toxicity data on the drug. (3 words)
1.) Data obtained from existing records or data sources. (2 words)
Data collected through techniques such as self-reported observations and biological assessments that are used to address a particular research question. (2 words)
Observational study wherein two groups, exposed and unexposed, are followed over a period of time until the development of the outcome of interest. (2 words)
The process of assigning patients to a treatment or control group randomly (i.e., by chance alone).
The overall plan that enables researchers to gather answers to study questions and test hypotheses. (2 words)
Down
A set of ideas that seeks to provide an understanding or explanation of natural phenomenon.
Systematic differences in data collection between study groups regarding how the exposures and outcomes are measured or reported by study participants, care givers, or researchers. Also called measurement bias. (2 words)
A descriptive study that tracks patients with a known exposure given similar treatment or that examines their medical records for exposure and outcome. (2 words
Modification in a study subject’s behavior because of the fact that he or she is being studied or observed. (2 words)
Research design that ensures that each subject receives all of the interventions based on a specified sequence of events. (2 words)
Experimental trial that is designed to demonstrate efficacy in a statistically powered sample of subjects with the disease in question. (3 words)
Bias that occurs when the exposure affects the diagnosis and hence the selection of cases in a case-control study. (2 words)
Experimental trial that involves the testing of a drug in humans with the intent of establishing the initial toxicity profile of the substance. (3 words)
Report that articulates the fundamental ethical principles that underpin all
The part of a research report or journal article that provides a description of the research design, data collection methods, and statistical tests used in an investigation. (2 words)
Ethical principle guiding human subjects research that refers to the moral requirement for fair procedures and outcomes in the selection of research subjects.