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Chapter 12 - The Elements of Chemotherapy

Across
Human based substance that targets viral infections
Treats middle ear, respiratory, and skin infections and have also been approved for tuberculosis in AIDS patients
Targets gram-positive and gram-negative rods and cocci, aerobic and anaerobic bacteria, mycoplasmas, rickettsias, and spirochetes
Targets the bacterial cell wall and many bacteria produce enzymes that can target the beta-lactam ring
Nutrients that encourage the growth of beneficial microbes in the gut
A drug that is chemically altered in a lab from a natural source
Powerful but dangerous drug and is only used when other drugs aren't working
Causes fewer allergic reactions than penicillin and is administered parenterally
An inheritable change in the DNA
Can develop because of mutations in chromosomal genes or horizontal gene transfer
Synthetic drug that inhibits the initiation of protein synthesis
Population of microbes can harbor bacteria that are drug resistant and these microbes can become the dominant microbes of the population
Difficult to treat because the cells are very similar to human cells because they are eukaryotic
Down
Agar diffusion test that determines the effectiveness of antimicrobials
Antimicrobial effective against both Gram-positive and Gram-negative bacteria
Typically used in combination therapy and inhibits the enzymatic step following the step inhibited by sulfonamides in the synthesis of folic acid
Inhibits RNA polymerase and mostly targets Gram-positive bacteria
Ratio of the toxic dose of a drug to its minimum inhibitory concentration
A primary infection is treated but drug resistant microbes can cause a different infection
Consists of one or more amino sugars and an aminocyclitol ring
Targets the cell membrane of Gram-negative bacilli
Used in combination therapy to treat tuberculosis