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Exam 2 Prep 2023

Across
Protease Inhibitor
Activates GLP-1 receptor on pancreatic beta cells
BMI is considered when prescribing
Produces 20% weight loss.
SGLT2 inhibitors are now recommended to be held 3-4 days before surgery due to increased risk of _________.
TZD binding site
Postmarket Warning for SGLT2 inhibitors
Class of drugs that inhibit carbohydrate metabolism
Metformin's risk of lactic acidosis is tripled when this lab value decreases to < 30 ml/min (abbreviation)
This enzyme breaks down 96% of your natural incretin hormone production.
In gestational diabetes the _____________ goal at 2 hours is lower than in type 2 diabetes at < 120 mg/dL (hyph).
Down
GIP-1 and ____-1 are considered incretin hormones.
Half-life of glucose biomarker
The biggest contraindication for GLP-1 agonists is a family history or personal history of cancer of the ______.
Selectively inhibits this transporter.
Derived from apple roots
Binds to SUR1 and SUR2A
SGLT2 inhibitors block re-absorption of glucose in this organ
This diabetes treatment agent is available as both a weekly injectable and an oral medication
Controls lipid metabolism by binding to a transcription factor.
This agent is considered the best insulin sensitizer, but has unfavorable side effects including HF exacerbations and osteoporosis.
Due to dehydration risk which of the following would be recommended to drink at least 8 oz of additional water when taking: Rosiglitazone or Canagliflozin
This drug specifically has indications for prevention of CKD progression as well as decreases in HF exacerbations even in those without diabetes.
Which of the following would you expect to have an A1c lowering of just 0.5-1%: Sitagliptin or Dulaglutide
This GLP-1 agonist is the only one with an official indication to improve CV mortality.
This medication has the least amount of active metabolites when metabolized through the liver so is considered the safest sulfonylurea for elderly patients
Metformin is an example of this class of drugs