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Midterm 2 Study Guide

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Across
4
CTLs produce this and it can bind to cell membranes and drill holes in them
7
T cells that have TCR molecules and express both CD4 and CD8 co-receptors on their surface are known as ______ positive cells.
8
This class of molecules display antigens that are present outside of the cell
11
This class of molecules display antigens that are present inside of the cell, and these molecules are present on virtually all somatic cells
13
The process where an activated B cell changes its antibody production from IgM to either IgA, IgG, or IgE
14
A cell can die two ways: necrosis and ________
15
The lymph nodes, spleen, and mucosal-associated lymphoid tissue are all ________ lymphoid organs
16
This protein on inflammed tissues binds to PD-1 on T cells and stops them from proliferating (no hyphen in answer)
17
A word that translates to self-eating, and functions as a survival tool to help cells deal with times of famine
18
Type of signal calling by Th cells that was first observed by Robert Koch when studying Tuberculosis: ___________hypersensitivity
Down
1
Tiny region of the cognate antigen that a BCR binds to
2
All secondary lymphoid organs share this anatomical feature in common: lymphoid _______
3
Helper T cells that remain 'unbiased' and can produce a wide range of cytokines
5
Cytokine that induces the proliferation of killer T cells (do not include the hyphen)
6
CD4 and CD8 are examples of a ______
7
These cells have a starfish-like shape and are known for taking snapshots of the battle field to present to T cells
9
These cells display one or the other of the co-receptor molecuels-- either CD4 or CD8
10
When a virgin T cell recognizes its cognate antigen presented on a cell but does not recieve the co-stimulation, the cell is said to be _________
12
Engagement of this receptor represses the activation by antagonizing the CD28 signal within a T cell (no hyphen in answer)
16
The process of testing T cells for MHC selection is usually referred to as ______ selection