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Pediatric Oncology

Across
Arises from ependymal cells and histology shows perivascular pseudorosettes.
Occurs in the metaphysis on long bones.
Well circumscribed, solid cystic lesion in the cerebellum with rosenthal fibers, and is GFAP+.
Associated with Osteosarcoma and causes leukoria in children.
Responds to all trans retinoic acid and involves t(15;17)
Brain tumor found in the cerebellum that shows homer wright rosettes on histology,
Down
Brain tumor that supresses the superior colliculus causing Parinaud Syndrome.
Occurs on the diaphysis of long bones, and deals with a mutation on chromosome 22.
Tumor involving overexpression and amplification of the N-MYC gene.
Appears as a supratentorial mass with a brown/yellow machine oil like consistency.
Presents as an abdominal mass that does NOT cross the midline, and can rupture causing subscapular hemorrhage.
Most common childhood leukemia and is associated with down syndrome.