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Rare Disease Week 2022

Welcome to Rare Disease Week 2022!
If you finish this crossword puzzle, you will receive one raffle ticket.
Across
A disorder that affects the spleen and is common in India and Japan. Main symptom is spleen enlargement.
This disease affects the insulating material in our brain, due to the mutation in a gene called GFAP.
The name of this syndrome is the acronym of its 4 symptoms. May also include seizures.
Symptoms include jerky movements of the arms and legs, happy disposition, and unprovoked episodes of laughter and smiling.
This is a rare disease in children less than one year old and can cause sudden infant death.
Down
A cardiovascular disorder caused by mutation in the SCN5A gene that encodes for the sodium channels in the heart. Symptoms include irregular heartbeat, trouble breathing, fainting, and can lead to sudden death.
Partial deletion of the short arm of chromosome 5 with a characteristic high-pitched, shrill cry that resembles the mewing of a cat.
A type of lung infection caused by a yeast-like fungus called Pneumocytis jirovecii. Treatment is antibiotics such as Bactrim.
Build up of fat called phytanic acid in blood plasma and tissue. Phytanic acid is a type of fatty acid which is derived by bacterial fermentation of green plants or algae.